Using circular RNA as a novel type of biomarker in the screening of gastric cancer.

@article{Li2015UsingCR,
  title={Using circular RNA as a novel type of biomarker in the screening of gastric cancer.},
  author={Peifei Li and Shengcan Chen and Huilin Chen and Xiaoyan Mo and Tianwen Li and Yongfu Shao and Bingxiu Xiao and Junming Guo},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2015},
  volume={444},
  pages={132-6}
}
BACKGROUND Circular RNAs (circRNAs), a class of endogenous RNAs, have emerged as an enigmatic class of RNAs. Little is known about their value in the diagnosis of cancers. METHODS The targeted circRNA of this study was selected using two circRNA databases: CircBase (http://circbase.org/) and circ2Traits (http://gyanxet-beta.com/circdb/). Divergent primers, rather than commonly used convergent primers, for the circRNA were designed. The circRNA levels in 101 paired gastric cancer tissues and… CONTINUE READING