Using case-control studies to assess the prevention of inflicted traumatic brain injury.

@article{Shapiro2008UsingCS,
  title={Using case-control studies to assess the prevention of inflicted traumatic brain injury.},
  author={Eugene D. Shapiro},
  journal={American journal of preventive medicine},
  year={2008},
  volume={34 4 Suppl},
  pages={S153-6}
}
Because the incidence of inflicted traumatic brain injury (inflicted TBI) is low, even in populations at increased risk, very large samples are necessary to have adequate statistical power to conduct a randomized clinical trial of the effectiveness of a potential intervention to prevent inflicted TBI. This requirement for large samples, in addition to the logistic demands of prospective clinical trials, makes it prohibitively expensive to conduct such studies. Case-control studies provide a… CONTINUE READING

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