Using animal models to develop therapeutics for Tourette Syndrome.

  title={Using animal models to develop therapeutics for Tourette Syndrome.},
  author={Neal R. Swerdlow and Ashley N Sutherland},
  journal={Pharmacology & therapeutics},
  volume={108 3},
The science of Tourette Syndrome (TS) is advancing at multiple levels of analysis and will be enhanced through the use of animal models. Particular challenges in the development of TS animal models reflect complex features of this disorder, including its waxing and waning course and its "invisible" sensory and psychic symptoms. Animal models can achieve face, predictive, or construct validity based on their particular features. Predictive validity, of most direct relevance to drug development… CONTINUE READING

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