Using a Péclet number for the translocation of a polymer through a nanopore to tune coarse-grained simulations to experimental conditions.

@article{Haan2015UsingAP,
  title={Using a P{\'e}clet number for the translocation of a polymer through a nanopore to tune coarse-grained simulations to experimental conditions.},
  author={Hendrick W de Haan and David Sean and Gary W. Slater},
  journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
  year={2015},
  volume={91 2},
  pages={022601}
}
Coarse-grained simulations are often employed to study the translocation of DNA through a nanopore. The majority of these studies investigate the translocation process in a relatively generic sense and do not endeavor to match any particular set of experimental conditions. In this manuscript, we use the concept of a Péclet number for translocation, P(t), to compare the drift-diffusion balance in a typical experiment vs a typical simulation. We find that the standard coarse-grained approach… CONTINUE READING