Using Sequence-Specific Chemical and Structural Properties of DNA to Predict Transcription Factor Binding Sites

Abstract

An important step in understanding gene regulation is to identify the DNA binding sites recognized by each transcription factor (TF). Conventional approaches to prediction of TF binding sites involve the definition of consensus sequences or position-specific weight matrices and rely on statistical analysis of DNA sequences of known binding sites. Here, we… (More)
DOI: 10.1371/journal.pcbi.1001007

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@inproceedings{Bauer2010UsingSC, title={Using Sequence-Specific Chemical and Structural Properties of DNA to Predict Transcription Factor Binding Sites}, author={Amy L. Bauer and William S. Hlavacek and Pat J. Unkefer and Fangping Mu}, booktitle={PLoS Computational Biology}, year={2010} }