Using RNA inverse folding to identify IRES-like structural subdomains

@article{Dot2013UsingRI,
  title={Using RNA inverse folding to identify IRES-like structural subdomains},
  author={Iv{\'a}n Dot{\'u} and Gloria Lozano and Peter Clote and Encarnaci{\'o}n Mart{\'i}nez-Salas},
  journal={RNA Biology},
  year={2013},
  volume={10},
  pages={1842 - 1852}
}
Internal ribosome entry site (IRES) elements govern protein synthesis of mRNAs that bypass cap-dependent translation inhibition under stress conditions. Picornavirus IRES are cis-acting elements, organized in modular domains that recruit the ribosome to internal mRNA sites. The aim of this study was to retrieve short RNA sequences with the capacity to adopt RNA folding patterns conserved with IRES structural subdomains, likely corresponding to RNA modules. We have applied a new program… 
Structural insights into viral IRES-dependent translation mechanisms.
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