Using ProHits to store, annotate, and analyze affinity purification-mass spectrometry (AP-MS) data.

@article{Liu2012UsingPT,
  title={Using ProHits to store, annotate, and analyze affinity purification-mass spectrometry (AP-MS) data.},
  author={Guomin Liu and Jianping Zhang and Hyungwon Choi and Jean-Philippe Lambert and Tharan Srikumar and Brett W. Larsen and Alexey I. Nesvizhskii and Brian Raught and Mike Tyers and Anne-Claude Gingras},
  journal={Current protocols in bioinformatics},
  year={2012},
  volume={Chapter 8},
  pages={Unit8.16}
}
Affinity purification coupled with mass spectrometry (AP-MS) is a robust technique used to identify protein-protein interactions. With recent improvements in sample preparation, and dramatic advances in MS instrumentation speed and sensitivity, this technique is becoming more widely used throughout the scientific community. To meet the needs of research groups both large and small, we have developed software solutions for tracking, scoring and analyzing AP-MS data. Here, we provide details for… CONTINUE READING

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