Using Non-steroidal Anti-inflammatory Drugs in the Treatment of Depression

  title={Using Non-steroidal Anti-inflammatory Drugs in the Treatment of Depression},
  author={Abigail Davis and Michael James Gilhooley and M. Agius},
  journal={Psychiatria Danubina},
  volume={22 Suppl 1},
BACKGROUND clinicians have long noticed a correlation between physiological markers of inflammation and depression. The best-known example is the activation of the hypothalamus-pituitary-adrenal axis and cortisol secretion; however more recent studies have demonstrated increased salivary prostaglandins and plasma acute phase proteins in depressed patients. To date four randomised controlled trials have used celecoxib or rofecoxib as adjuncts to serotonin selective reuptake inhibitors in the… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 13 references

Depression in Adults

  • Excellence NIfC
  • NICE Guidelines
  • 2009

Similar Papers

Loading similar papers…