Using DNA Duplex Stability Information for Transcription Factor Binding Site Discovery

Abstract

Transcription factor (TF) binding site discovery is an important step in understanding transcriptional regulation. Many computational tools have already been developed, but their success in detecting TF motifs is still limited. We believe one of the main reasons for the low accuracy of current methods is that they do not take into account the structural… (More)

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@article{Gordn2008UsingDD, title={Using DNA Duplex Stability Information for Transcription Factor Binding Site Discovery}, author={Raluca Gord{\^a}n and Alexander J. Hartemink}, journal={Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing}, year={2008}, pages={453-64} }