Uses and complications of isotretinoin therapy.

  title={Uses and complications of isotretinoin therapy.},
  author={Charles N. Ellis and Katrin Krach},
  journal={Journal of the American Academy of Dermatology},
  volume={45 5},
Isotretinoin (13-cis-retinoic acid) is a retinoid that has been used over the past 2 decades to treat a wide variety of dermatologic conditions, some with great success. Although it is beneficial in many skin conditions, the side effects and toxicities of oral retinoids require careful monitoring by experienced physicians. The clinical applications of oral retinoids continue to expand both within and beyond the field of dermatology.