Usefulness of procalcitonin serum level for the discrimination of severe sepsis from sepsis: a multicenter prospective study.

@article{Endo2008UsefulnessOP,
  title={Usefulness of procalcitonin serum level for the discrimination of severe sepsis from sepsis: a multicenter prospective study.},
  author={Shigeatsu Endo and Naoki Aikawa and Seitaro Fujishima and Isao Sekine and Kazuhiro Kogawa and Yasuhiro Yamamoto and Shigeki Kushimoto and Hidekazu Yukioka and Noboru Kato and Kyoichi Totsuka and Ken Kikuchi and Toshiaki Ikeda and Kazumi Ikeda and Hiroyuki Yamada and Kazuaki Harada and Shinji Satomura},
  journal={Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy},
  year={2008},
  volume={14 3},
  pages={244-9}
}
Procalcitonin serum level has been recommended as a new marker of bacterial infectious diseases. The aim of this prospective, multicenter study was to determine the clinical usefulness of procalcitonin in differentiating patients with sepsis from those with severe sepsis. Eighty-two patients were enrolled: 20 without systemic inflammatory response syndrome (SIRS), 9 with SIRS, 34 with sepsis, and 19 with severe sepsis. The patients with severe sepsis had significantly higher procalcitonin… CONTINUE READING

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