Usefulness of intramyocardial injection of autologous bone marrow-derived mononuclear cells in patients with severe angina pectoris and stress-induced myocardial ischemia.

@article{Beeres2006UsefulnessOI,
  title={Usefulness of intramyocardial injection of autologous bone marrow-derived mononuclear cells in patients with severe angina pectoris and stress-induced myocardial ischemia.},
  author={Saskia L. M. A. Beeres and Jeroen J. Bax and Theodorus Kaandorp and Katja Zeppenfeld and Hildo J. Lamb and Petra Dibbets-Schneider and Marcel P. M. Stokkel and Willem E. Fibbe and Albert de Roos and E. E. van der Wall and Martin Jan Schalij and Douwe Ekke Atsma},
  journal={The American journal of cardiology},
  year={2006},
  volume={97 9},
  pages={1326-31}
}
Bone marrow cell transplantation has been proposed as a novel therapeutic option for patients with coronary artery disease. This study investigated whether autologous bone marrow-derived mononuclear cell injection into the ischemic myocardium of patients with severe angina pectoris could safely reduce anginal symptoms, improve myocardial perfusion, and increase left ventricular (LV) function. In a total of 20 patients (63 +/- 10 years old; 16 men) with angina pectoris, myocardial segments with… CONTINUE READING
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