Effect of Supranutritional Organic Selenium Supplementation on Postpartum Blood Micronutrients, Antioxidants, Metabolites, and Inflammation Biomarkers in Selenium-Replete Dairy Cows
Stress often results in the increased production of free radicals in organisms. Recent studies have indicated an interesting relationship between the presence of reactive oxigen species (ROS) and specific cellular activities in the mammary gland of lactating sheep (Colitti et al., 2002), and immunological activity (Kimura et al., 1999) and the ovarian cycle in dairy cows (Trout et al., 1998). An alternative strategy in the control of ROS generation, apart from vitamin E and C administration, is the inclusion in the diet of active compounds such as carotenoids and polyphenols (Jewell and O’Brien, 1999). The role and the activity of natural antioxidants not commonly present in the diets of ruminants (carotenoids and polyphenols of fruits) in the control of ROS generation is an interesting topic to investigate. The aim of this study was to evaluate the effects of dietary administration of nutraceutics with antioxidant properties, in the regulation of cellular redox homeostasis in ruminants.