Use of yeast artificial chromosome clones for mapping and walking within human chromosome segment 18q21.3.

Abstract

Well-characterized large genomic clones obtained from yeast artificial chromosome (YAC) libraries provide the framework to localize genes and approach genetic disease. We developed universally applicable approaches to establish authenticity, localize and orient internal genes, map restriction sites, and rescue the distal ends of large human genomic DNA… (More)

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@article{Silverman1989UseOY, title={Use of yeast artificial chromosome clones for mapping and walking within human chromosome segment 18q21.3.}, author={Gary A. Silverman and Richard Dequan Ye and Katrina M. Pollock and J Evan Sadler and S Stanley J. Korsmeyer}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1989}, volume={86 19}, pages={7485-9} }