Use of twin cohorts for research in Alzheimer's disease.

  title={Use of twin cohorts for research in Alzheimer's disease.},
  author={John C. S. Breitner and Maragaret Gatz and Astrid Liv Mina Bergem and Joe C. Christian and James A. Mortimer and Gerald E Mcclearn and Leonard L. Heston and Kathleen A Welsh and James Christopher Anthony and Marshal F. Folstein},
  volume={43 2},
The causes of Alzheimer's disease (AD) remain a mystery despite the recent identification of several putative environmental risk factors and the discovery of several linked genetic loci and point mutations associated with the disease. Particularly uncertain is the generalizability of the genetic findings to the common forms of disease encountered in clinical practice or population research. Twin studies of AD can illuminate causal mechanisms, both genetic and environmental. This consensus… CONTINUE READING

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