Use of tissue recombination to predict phenotypes of transgenic mouse models of prostate carcinoma

Abstract

Transgenic mouse models of cancer represent a powerful approach for exploring disease processes and testing potential therapeutic interventions. Currently, it is difficult to predict if a specific genetic manipulation will result in a desirable phenotype. The present study tests the idea that tissue recombinants recapitulate the pathologic features of the… (More)
DOI: 10.1038/labinvest.3700310

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