Use of thiopurines in the treatment of inflammatory bowel disease is associated with an increased risk of non-melanoma skin cancer in an at-risk population: a cohort study.

@article{Setshedi2012UseOT,
  title={Use of thiopurines in the treatment of inflammatory bowel disease is associated with an increased risk of non-melanoma skin cancer in an at-risk population: a cohort study.},
  author={Mashiko Setshedi and David K Epstein and Trevor A. Winter and Landon Myer and Gillian Ann Watermeyer and Richard J. Hift},
  journal={Journal of gastroenterology and hepatology},
  year={2012},
  volume={27 2},
  pages={385-9}
}
BACKGROUND AND AIM The thiopurines azathioprine and 6-mercaptopurine are effective in the management of patients with inflammatory bowel disease (IBD) in whom aminosalicylates, antibiotics and corticosteroids have failed to induce or maintain remission. Long-term use of these agents has been linked to a greatly increased risk of non-melanoma skin cancer and lymphatic cancer in organ transplant recipients. There is some evidence to suggest that IBD patients receiving thiopurines might be at… CONTINUE READING

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