Use of the urine cortisol: creatinine ratio to monitor treatment response in dogs with pituitary-dependent hyperadrenocorticism.


OBJECTIVE To determine the usefulness of measuring urine cortisol:creatinine ratio (UCCR) as a means of monitoring response to mitotane treatment in dogs with pituitary-dependent hyperadrenocorticism (PDH). DESIGN Case series. ANIMALS 51 clinically normal dogs and 21 dogs with PDH. PROCEDURE The reference range for the UCCR was determined by measuring… (More)