Use of the low-molecular-weight heparin reviparin to prevent deep-vein thrombosis after leg injury requiring immobilization.

@article{Lassen2002UseOT,
  title={Use of the low-molecular-weight heparin reviparin to prevent deep-vein thrombosis after leg injury requiring immobilization.},
  author={Michael Rud Lassen and Lars Carl Borris and Roumen L Nakov},
  journal={The New England journal of medicine},
  year={2002},
  volume={347 10},
  pages={726-30}
}
BACKGROUND Deep-vein thrombosis is a well-recognized complication after trauma to the legs and subsequent immobilization, but there are no generally accepted approaches to preventing this complication. METHODS We performed a prospective, double-blind, placebo-controlled trial to evaluate the efficacy and safety of subcutaneous reviparin (1750 anti-Xa units given once daily) in 440 patients who required immobilization in a plaster cast or brace for at least five weeks after a leg fracture or… CONTINUE READING

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