Use of the combined first-trimester screen result and low PAPP-A to predict risk of adverse fetal outcomes.

@article{Barrett2008UseOT,
  title={Use of the combined first-trimester screen result and low PAPP-A to predict risk of adverse fetal outcomes.},
  author={Sandie L Barrett and Carol Bower and Narelle Hadlow},
  journal={Prenatal diagnosis},
  year={2008},
  volume={28 1},
  pages={28-35}
}
OBJECTIVES To investigate associations between combined first-trimester screen result, pregnancy associated plasma protein-A (PAPP-A) level and adverse fetal outcomes in women. METHODS Pregnancy outcomes for 10,273 women participating in a community based first-trimester screening (FTS) programme in Western Australia were ascertained by record linkage to birth and birth defect databases. A first-trimester risk cut-off of > or = 1 in 300 defined screen positive women. RESULTS Screen positive… CONTINUE READING

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