Use of the Gibbs sampler to estimate transition rates between grades of coronary disease following cardiac transplantation.

@article{Sharples1993UseOT,
  title={Use of the Gibbs sampler to estimate transition rates between grades of coronary disease following cardiac transplantation.},
  author={Linda D. Sharples},
  journal={Statistics in medicine},
  year={1993},
  volume={12 12},
  pages={1155-69}
}
Coronary occlusive disease following cardiac transplantation is monitored using serial angiography, and graded on a 3 point scale according to the amount of narrowing observed in major vessels. Disease progression is modelled as a continuous time Markov process. The Gibbs sampler is used to estimate the marginal posterior distributions of the transition rates between grades of disease and from each grade to death.