Use of the γH2AX assay for assessing the genotoxicity of bisphenol A and bisphenol F in human cell lines
@article{Audebert2011UseOT, title={Use of the $\gamma$H2AX assay for assessing the genotoxicity of bisphenol A and bisphenol F in human cell lines}, author={Marc Audebert and Laurence Dolo and Elisabeth Perdu and Jean-Pierre Cravedi and Daniel Zalko}, journal={Archives of Toxicology}, year={2011}, volume={85}, pages={1463-1473} }
Bisphenol A (BPA) and bisphenol F (BPF) are widely used to manufacture plastics and epoxy resins. Both compounds have been shown to be present in the environment and are food contaminants, with, as a result, a low but chronic exposure of humans. However, the fate and possible bioactivation of these compounds at the level of human cell lines was not completely elucidated yet. In this study, we investigated the ability of human cells (intestinal cell line: LS174T, hepatoma cell line: HepG2, and…
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