Use of tetramethylbenzidine in plasma hemoglobin assay.

@article{Standefer1977UseOT,
  title={Use of tetramethylbenzidine in plasma hemoglobin assay.},
  author={Jimmy C Standefer and Dorothy Joan Vanderjagt},
  journal={Clinical chemistry},
  year={1977},
  volume={23 4},
  pages={749-51}
}
Plasma hemoglobin can be assayed by substituting 3,3',5,5'-tetramethylbenzidine for benzidine (a carcinogen) as the chromogenic reducing substance. Sensitivity, precision, and accuracy compare well with methods in which benzidine is used. Plasma inhibition can be accommodated by preincubation with hydrogen peroxide.