Use of surrogate outcomes in cost-effectiveness models: a review of United Kingdom health technology assessment reports.

@article{Elston2009UseOS,
  title={Use of surrogate outcomes in cost-effectiveness models: a review of United Kingdom health technology assessment reports.},
  author={Julian Elston and R. S. L. Taylor},
  journal={International journal of technology assessment in health care},
  year={2009},
  volume={25 1},
  pages={6-13}
}
OBJECTIVES The aim of this study was to explore the use of surrogate outcomes--a substitute outcome that predicts final patient-related outcomes--in cost-effectiveness models (CEM) within health technology assessment (HTA) reports and provide guidance for their future use. METHODS Our sampling frame was all UK HTA Program monograph series reports published in 2005 and 2006. Reports were included if they addressed a treatment effectiveness/efficacy question and included a CEM based on a… CONTINUE READING

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