Use of streptococcal protein G in obtaining crystals of an antibody Fab fragment in complex with a meningococcal antigen.

@article{Derrick1999UseOS,
  title={Use of streptococcal protein G in obtaining crystals of an antibody Fab fragment in complex with a meningococcal antigen.},
  author={Jeremy P Derrick and Ian M. Feavers and Martin C J Maiden},
  journal={Acta crystallographica. Section D, Biological crystallography},
  year={1999},
  volume={55 Pt 1},
  pages={314-6}
}
Crystals have been obtained of an antibody Fab fragment grown in the presence of a single domain from streptococcal protein G and a ten amino-acid peptide corresponding to the P1.7 serosubtype antigen from the human pathogen Neisseria meningitidis. Crystal trials using the Fab fragment and peptide antigen alone were unsuccessful, but the inclusion of a… CONTINUE READING