Use of sirolimus in liver transplant recipients with renal insufficiency: a systematic review and meta-analysis.

UNLABELLED Sirolimus is used in patients with renal insufficiency after liver transplantation (LT) and especially in those with calcineurin inhibitor (CNI)-associated nephrotoxicity. We conducted a systematic review of all randomized controlled trials and observational studies to test the hypothesis that the use of sirolimus is associated with an… (More)