Use of single-dose nevirapine for the prevention of mother-to-child transmission of HIV-1: does development of resistance matter?

@article{Mcconnell2007UseOS,
  title={Use of single-dose nevirapine for the prevention of mother-to-child transmission of HIV-1: does development of resistance matter?},
  author={Michelle S. Mcconnell and Jeffrey S. A. Stringer and Athena P. Kourtis and Paul J. Weidle and Susan H Eshleman},
  journal={American journal of obstetrics and gynecology},
  year={2007},
  volume={197 3 Suppl},
  pages={S56-63}
}
Nevirapine resistance has been detected in a considerable proportion of women after single-dose nevirapine (SD-NVP) for the prevention of mother-to-child human immunodeficiency virus-1 transmission. As a result, concern has been raised about the effectiveness of subsequent nevirapine-based treatment. Studies in Thailand, Botswana, and South Africa have assessed virologic treatment response after SD-NVP. These studies did not find any significant difference in virologic response for women who… CONTINUE READING

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