Use of simple noninvasive biomarkers to predict liver fibrosis in HIV/HCV coinfection in routine clinical practice.

@article{Macas2010UseOS,
  title={Use of simple noninvasive biomarkers to predict liver fibrosis in HIV/HCV coinfection in routine clinical practice.},
  author={Juan Mac{\'i}as and Juan Gonzalez and Enrique Ortega and Cristina Tural and Esther Cabrero and Angel Burgos and Juan A Pineda},
  journal={HIV medicine},
  year={2010},
  volume={11 7},
  pages={439-47}
}
BACKGROUND Simple noninvasive tests to predict fibrosis, as an alternative to liver biopsy (LB), are needed. Of these, the aspartate aminotransferase (AST) to platelet ratio index (APRI) and the Forns index (FI) have been validated in HIV/hepatitis C virus (HCV) coinfection. However, these indexes may have lower diagnostic value in situations other than the circumscribed conditions of validation studies. We therefore examined the value of the APRI and FI in HIV/HCV-coinfected patients for the… CONTINUE READING
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