Use of serum biomarkers to predict cerebral hypoxia after severe traumatic brain injury.

@article{Stein2012UseOS,
  title={Use of serum biomarkers to predict cerebral hypoxia after severe traumatic brain injury.},
  author={Deborah M. Stein and Allison L Lindell and Karen R Murdock and Joseph A. Kufera and Jay A Menaker and Grant V. Bochicchio and Bizhan Aarabi and Thomas M. Scalea},
  journal={Journal of neurotrauma},
  year={2012},
  volume={29 6},
  pages={1140-9}
}
The management of severe traumatic brain injury (TBI) focuses on prevention and treatment of secondary insults such as cerebral hypoxia (CH). There are a number of biomarkers that are thought to play a part in secondary injury following severe TBI. This study evaluates the association between S100β, neuron-specific enolase (NSE), and glial fibrillary acidic protein (GFAP), detected in the serum of severe TBI patients and CH as measured by brain tissue oxygen partial pressure (Pbo(2)). Patients… CONTINUE READING

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