Use of selective serotonin reuptake inhibitors and risk of upper gastrointestinal bleeding: a systematic review and meta-analysis.


BACKGROUND & AIMS Selective serotonin reuptake inhibitors (SSRIs) are used to treat various psychiatric disorders. However, there are concerns that SSRIs increase the risk for upper gastrointestinal bleeding (UGIB). METHODS We performed a systematic review and meta-analysis of controlled observational studies to determine whether SSRI use affects the risk… (More)
DOI: 10.1016/j.cgh.2014.06.021


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