Use of selective antagonists for determining the types of receptors mediating the actions of 5-hydroxytryptamine and tryptamine in the isolated rabbit aorta.

Abstract

Competitive and noncompetitive antagonists were used to study the receptors which mediate the contraction elicited by 5-hydroxytryptamine (5-HT) and tryptamine (TRP) in the isolated rabbit aorta. The response to 5-HT was more susceptible to inhibition by competitive antagonists selective for 5-HT receptors, such as cyproheptadine, 5-methylgramine, 5… (More)

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@article{Stollak1983UseOS, title={Use of selective antagonists for determining the types of receptors mediating the actions of 5-hydroxytryptamine and tryptamine in the isolated rabbit aorta.}, author={J S Stollak and Robert F. Furchgott}, journal={The Journal of pharmacology and experimental therapeutics}, year={1983}, volume={224 1}, pages={215-21} }