Use of recombinant activated factor VII in patients with Glanzmann's thrombasthenia: a review of the literature.

@article{Rajpurkar2014UseOR,
  title={Use of recombinant activated factor VII in patients with Glanzmann's thrombasthenia: a review of the literature.},
  author={Madhvi Rajpurkar and Meera B Chitlur and Michael P. Recht and David L Cooper},
  journal={Haemophilia : the official journal of the World Federation of Hemophilia},
  year={2014},
  volume={20 4},
  pages={464-71}
}
Glanzmann's thrombasthenia (GT) is a rare bleeding disorder characterized by a quantitative or qualitative defect of glycoprotein IIb/IIIa on the platelet membrane. Managing bleeding episodes is often difficult, and a variety of modalities have been used, including platelet transfusions, recombinant factor VIIa (rFVIIa), and other supportive care. The aim of this review was to present the clinical experience with rFVIIa bolus infusion (rFVIIa BI) for treatment of bleeding episodes and… CONTINUE READING

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Managing bleeding episodes is often difficult , and a variety of modalities have been used , including platelet transfusions , recombinant factor VIIa ( rFVIIa ) , and other supportive care .
Managing bleeding episodes is often difficult , and a variety of modalities have been used , including platelet transfusions , recombinant factor VIIa ( rFVIIa ) , and other supportive care .
Glanzmann 's thrombasthenia ( GT ) is a rare bleeding disorder characterized by a quantitative or qualitative defect of glycoprotein IIb / IIIa on the platelet membrane .
Glanzmann 's thrombasthenia ( GT ) is a rare bleeding disorder characterized by a quantitative or qualitative defect of glycoprotein IIb / IIIa on the platelet membrane .
Glanzmann 's thrombasthenia ( GT ) is a rare bleeding disorder characterized by a quantitative or qualitative defect of glycoprotein IIb / IIIa on the platelet membrane .
The aim of this review was to present the clinical experience with rFVIIa bolus infusion ( rFVIIa BI ) for treatment of bleeding episodes and prevention of bleeding during surgical procedures in patients with GT .
Glanzmann 's thrombasthenia ( GT ) is a rare bleeding disorder characterized by a quantitative or qualitative defect of glycoprotein IIb / IIIa on the platelet membrane .
Glanzmann 's thrombasthenia ( GT ) is a rare bleeding disorder characterized by a quantitative or qualitative defect of glycoprotein IIb / IIIa on the platelet membrane .
Glanzmann 's thrombasthenia ( GT ) is a rare bleeding disorder characterized by a quantitative or qualitative defect of glycoprotein IIb / IIIa on the platelet membrane .
Managing bleeding episodes is often difficult , and a variety of modalities have been used , including platelet transfusions , recombinant factor VIIa ( rFVIIa ) , and other supportive care .
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