Use of real-time PCR to rule out Marek's disease in the diagnosis of peripheral neuropathy.

@article{Gall2018UseOR,
  title={Use of real-time PCR to rule out Marek's disease in the diagnosis of peripheral neuropathy.},
  author={Sesny Gall and L{\'a}szl{\'o} Kőr{\"o}si and Aneg L. Cortes and Andrea Delvecchio and Francesco Prandini and P Mitsch and Isabel M. Gimeno},
  journal={Avian pathology : journal of the W.V.P.A},
  year={2018},
  volume={47 4},
  pages={
          427-433
        }
}
This article reports nine cases of neurological disease in brown layer pullets that occured in various European countries between 2015 and 2018. In all cases, the onset of neurological clinical signs was at 4-8 weeks of age and they lasted up to 22 weeks of age. Enlargement of peripheral nerves was the main lesion observed in all cases. Histopathological evaluation of nerves revealed oedema with moderate to severe infiltration of plasma cells. Marek's disease (MD) was ruled out by real-time PCR… CONTINUE READING
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