Use of radiolabeled monoclonal antibody to enhance vaccine-mediated antitumor effects


Radiolabeled monoclonal antibodies (mAb) have demonstrated measurable antitumor effects in hematologic malignancies. This outcome has been more difficult to achieve for solid tumors due, for the most part, to difficulties in delivering sufficient quantities of mAb to the tumor mass. Previous studies have shown that nonlytic levels of external beam radiation… (More)
DOI: 10.1007/s00262-008-0449-x


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