Use of rabies virus as a transneuronal tracer of neuronal connections: implications for the understanding of rabies pathogenesis.

@article{Ugolini2008UseOR,
  title={Use of rabies virus as a transneuronal tracer of neuronal connections: implications for the understanding of rabies pathogenesis.},
  author={Gabriella Ugolini},
  journal={Developments in biologicals},
  year={2008},
  volume={131},
  pages={493-506}
}
In neurosciences, rabies virus (CVS strain) has become a very powerful tool for studying multisynaptic neuronal connections, due to its ability to function as a self-replicating marker and to propagate exclusively between connected neurons by transneuronal transfer, which is strictly time-dependent. In this laboratory, transneuronal tracing studies of rabies virus propagation in primates and rodent models during the asymptomatic period have provided valuable information on rabies pathogenesis… CONTINUE READING

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