Use of proteomics to identify highly abundant maternal factors that drive the egg-to-embryo transition.

@article{Yurttas2010UseOP,
  title={Use of proteomics to identify highly abundant maternal factors that drive the egg-to-embryo transition.},
  author={Piraye Yurttas and Eric Morency and Scott A Coonrod},
  journal={Reproduction},
  year={2010},
  volume={139 5},
  pages={809-23}
}
As IVF becomes an increasingly popular method for human reproduction, it is more critical than ever to understand the unique molecular composition of the mammalian oocyte. DNA microarray studies have successfully provided valuable information regarding the identity and dynamics of factors at the transcriptional level. However, the oocyte transcribes and stores a large amount of material that plays no obvious role in oogenesis, but instead is required to regulate embryogenesis. Therefore, an… CONTINUE READING

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