Use of progestins in male contraception

@article{Nieschlag2003UseOP,
  title={Use of progestins in male contraception},
  author={E. Nieschlag and M. Zitzmann and A. Kamischke},
  journal={Steroids},
  year={2003},
  volume={68},
  pages={965-972}
}
Hormonal male contraception aims at suppression of spermatogenesis to azoospermia or at least to severe oligoasthenozoospermia, incompatible with the ability to induce a pregnancy. The general principle of this approach is based on interference with the endocrine regulation of spermatogenesis, i.e. the suppression of gonadotropins. Since both FSH (through the Sertoli cell) and LH (through the Leydig cell and testosterone (T)) are required for normal spermatogenesis, both gonadotropins need to… Expand
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