Use of plethysmography in assessing the efficacy of antivirals in a mouse model of pandemic influenza A virus.

Abstract

The recently emerged swine-origin H1N1 influenza A virus (IAV) caused a pandemic outbreak in 2009 with higher risk of severe disease among children and pregnant women in their third trimester (Van Kerkhove et al., 2011), and is continuing to be important seasonal IAV strain. Mice are commonly used in antiviral studies as models of influenza disease, which… (More)
DOI: 10.1016/j.antiviral.2011.08.011

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