Use of platelet lysate for bone regeneration - are we ready for clinical translation?

@article{Altaie2016UseOP,
  title={Use of platelet lysate for bone regeneration - are we ready for clinical translation?},
  author={A. Altaie and H. Owston and E. Jones},
  journal={World journal of stem cells},
  year={2016},
  volume={8 2},
  pages={
          47-55
        }
}
Current techniques to improve bone regeneration following trauma or tumour resection involve the use of autograft bone or its substitutes supplemented with osteoinductive growth factors and/or osteogenic cells such as mesenchymal stem cells (MSCs). Although MSCs are most commonly grown in media containing fetal calf serum, human platelet lysate (PL) offers an effective alternative. Bone marrow - derived MSCs grown in PL-containing media display faster proliferation whilst maintaining good… Expand
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