Use of plasma somatomedin-C/insulin-like growth factor I measurements to monitor the response to nutritional repletion in malnourished patients.

@article{Clemmons1985UseOP,
  title={Use of plasma somatomedin-C/insulin-like growth factor I measurements to monitor the response to nutritional repletion in malnourished patients.},
  author={David Robert Clemmons and Louis E. Underwood and Roland N. Dickerson and Rex Brown and Lawrence J. Hak and Ross D E MacPhee and William D. Heizer},
  journal={The American journal of clinical nutrition},
  year={1985},
  volume={41 2},
  pages={191-8}
}
Changes in plasma somatomedia-C/insulin-like growth factor I (Sm-C/IGF-I) concentrations are a sensitive indicator of the anabolic response of normal human volunteers to alterations in nutritional intake. To determine if measurement of this peptide could be used to monitor the response to nutritional repletion in malnourished patients, six patients were studied while receiving nutritional support for periods of 10-16 days. Plasma Sm-C/IGF-I increased from a mean basal level of 0.67 +/- 0.15 U… CONTINUE READING
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