Use of parallel validation high-throughput screens to reduce false positives and identify novel dengue NS2B-NS3 protease inhibitors.

Abstract

Dengue virus (DENV), a mosquito-borne member of the family Flaviviridae, is a significant global pathogen affecting primarily tropical and subtropical regions of the world and placing tremendous burden on the limited medical infrastructure that exists in many of the developing countries located within these regions. Recent outbreaks in developed countries… (More)
DOI: 10.1016/j.antiviral.2011.12.003

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@article{Tomlinson2012UseOP, title={Use of parallel validation high-throughput screens to reduce false positives and identify novel dengue NS2B-NS3 protease inhibitors.}, author={Suzanne M. Tomlinson and Stanley J. Watowich}, journal={Antiviral research}, year={2012}, volume={93 2}, pages={245-52} }