Use of oral proton pump inhibitors is not associated with harm in patients with chronic heart failure in an ambulatory setting.

@article{Oudit2011UseOO,
  title={Use of oral proton pump inhibitors is not associated with harm in patients with chronic heart failure in an ambulatory setting.},
  author={Gavin Yadram Oudit and Jeffrey A. Bakal and Finlay Aleck McAlister and Justin A Ezekowitz},
  journal={European journal of heart failure},
  year={2011},
  volume={13 11},
  pages={1211-5}
}
AIMS Proton pump inhibitors (PPIs) produce negative inotropic effects on the human myocardium at clinically relevant plasma concentrations. We conducted this study to determine whether PPI use was associated with excess mortality in patients with both ischaemic and non-ischaemic heart failure (HF). METHODS AND RESULTS The impact of PPIs on all-cause mortality was examined using a population-based cohort of Alberta residents over the age of 65 with a diagnosis of HF, logistic regression… CONTINUE READING