Use of once-daily netilmicin to treat infants with suspected sepsis in a neonatal intensive care unit.

@article{Brooks2004UseOO,
  title={Use of once-daily netilmicin to treat infants with suspected sepsis in a neonatal intensive care unit.},
  author={Jesse R. Brooks and Neil Marlow and Barnaby C Reeves and Michael R. Millar},
  journal={Biology of the neonate},
  year={2004},
  volume={86 3},
  pages={170-5}
}
Once-daily administration of aminoglycoside antibiotics has become the most acceptable dosing schedule for the majority of patients. There are few published data on the impact of post-natal age on aminoglycoside concentrations in preterm infants receiving once-daily dosage regimens. Netilmicin was administered as a once-daily dose of 4 mg/kg. In 141 episodes of suspected sepsis in 123 babies, trough netilmicin concentrations ranged from undetectable to 4.0 mg/l. Netilmicin concentrations were… CONTINUE READING

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