Use of old antibiotics now and in the future from a pharmacokinetic/pharmacodynamic perspective.

@article{Muller2015UseOO,
  title={Use of old antibiotics now and in the future from a pharmacokinetic/pharmacodynamic perspective.},
  author={Anouk E. Muller and Ursula Theuretzbacher and Johan W Mouton},
  journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases},
  year={2015},
  volume={21 10},
  pages={881-5}
}
Because of the increase in bacterial resistance to commonly used antibacterial drugs, old antibiotics are being 'revived' and, once again, are attracting interest. Many of these old antibiotics were approved long ago, in an era when there was no clear process for development, and requirements for efficacy to be demonstrated in rigorous clinical trials did… CONTINUE READING

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