Use of new oral anticoagulants in antiphospholipid syndrome.

  title={Use of new oral anticoagulants in antiphospholipid syndrome.},
  author={Deepa Ranjani Jayakody Arachchillage and Hannah Cohen},
  journal={Current rheumatology reports},
  volume={15 6},
The current mainstay of treatment of thrombotic APS is long-term anticoagulation with oral vitamin K antagonists (VKA) such as warfarin. However, the use of warfarin is problematic, particularly in patients with antiphospholipid syndrome (APS). The new oral anticoagulants (NOAC) include dabigatran etexilate (Pradaxa®), a direct thrombin inhibitor, and rivaroxaban (Xarelto®), Apixaban (Eliquis) and Edoxaban (Lixiana®), which are direct anti-Xa inhibitors. Unlike warfarin, these agents do not… CONTINUE READING
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