Use of mutants to establish (+)-scytalone as an intermediate in melanin biosynthesis by Verticillium dahliae.

@article{Bell1976UseOM,
  title={Use of mutants to establish (+)-scytalone as an intermediate in melanin biosynthesis by Verticillium dahliae.},
  author={Alois A. Bell and J E Puhalla and W J Tolmsoff and Robert D Stipanovic},
  journal={Canadian journal of microbiology},
  year={1976},
  volume={22 6},
  pages={787-99}
}
Melanin biosynthesis in Verticillium dahliae Kleb, was studied with mutants deficient for normal black melanin or for production of microsclerotia. Seven genetically different mutants had apparent blocks in melanin biosynthesis. Four mutants (brm-1 to -4) produced brown microsclerotia and extruded pigments into media; three (alm-1 to -3) produced albino microsclerotia. Other mutants produced no microsclerotia (nms) or had greatly reduced numbers of microsclerotia (rms). Mutation alm-1 was due… CONTINUE READING
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