Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation

@article{Stoler1988UseOM,
  title={Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation},
  author={Andrea Stoler and Raphael Kopan and Madeleine Duvic and Elaine Fuchs},
  journal={The Journal of Cell Biology},
  year={1988},
  volume={107},
  pages={427 - 446}
}
We report here the isolation and characterization of three antisera, each of which is specific for a single keratin from one of the three different pairs (K1/K10, K14/K5, K16/K6) that are differentially expressed in normal human epidermis and in epidermal diseases of hyperproliferation. We have used these antisera in conjunction with monospecific cRNA probes for epidermal keratin mRNAs to investigate pathways of differentiation in human epidermis and epidermal diseases in vivo and in epidermal… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 103 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 56 references

Experimental Stoler et al

  • J. Viac, M. J. Staquet, J. Thivolet, C. Goujon.
  • Keratin Expression in Epidermal Diseases
  • 1980
Highly Influential
5 Excerpts

Dermatology in General Medicine

  • T. B. Fitzpatrick, A. Z. Eisen, K. Wolff, I. M. Freedberg, K. F. Austen.
  • McGraw-Hill Inc., New York. 1884 pp.
  • 1979
Highly Influential
7 Excerpts

Similar Papers

Loading similar papers…