Use of monoclonal antibodies to analyse the expression of a multi-tubulin family.

  title={Use of monoclonal antibodies to analyse the expression of a multi-tubulin family.},
  author={Christopher R. Birkett and Katie Eloise Foster and Linda A. Johnson and Keith Gull},
  journal={FEBS letters},
  volume={187 2},
We have used a panel of monoclonal antibodies in a study of the expression of multiple tubulins in Physarum polycephalum. Three anti-beta-tubulin monoclonal antibodies, DM1B, DM3B3 and KMX-1 all reacted with the beta 1-tubulin isotypes expressed in both myxamoebae and plasmodia. However, these antibodies showed a spectrum of reduced reactivity with the plasmodial beta 2-tubulin isotype - the competence of recognition of this isotype was graded DM1B greater than KMX-1 greater than DM3B3. The… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 57 extracted citations

An Alternative Model for the Role of RP2 Protein in Flagellum Assembly in the African Trypanosome*

The Journal of biological chemistry • 2014
View 6 Excerpts
Highly Influenced

Gangliosides are important for the preservation of the structure and organization of RBL-2H3 mast cells.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society • 2010
View 2 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…