Use of metformin in polycystic ovary syndrome: a meta-analysis.

  title={Use of metformin in polycystic ovary syndrome: a meta-analysis.},
  author={Andreea A Creanga and Heather M. Bradley and Colleen McCormick and Catherine Takacs Witkop},
  journal={Obstetrics and gynecology},
  volume={111 4},
OBJECTIVE To update the state of evidence on the efficacy of metformin, used either alone or in combination with clomiphene citrate in women with polycystic ovary syndrome, by examining three outcomes: ovulation, pregnancy, and live birth. Sources of heterogeneity among the published randomized controlled trials are systematically assessed. DATA SOURCES An electronic literature search was performed using MEDLINE, EMBASE, SCOPUS, CENTRAL, Cochrane, and U.S. Food and Drug Administration… CONTINUE READING


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