Use of mercaptophenylboronic acid functionalized gold nanoparticles in a sensitive and selective dynamic light scattering assay for glucose detection in serum.

@article{Wang2013UseOM,
  title={Use of mercaptophenylboronic acid functionalized gold nanoparticles in a sensitive and selective dynamic light scattering assay for glucose detection in serum.},
  author={Qing Wang and Liyan Yang and Xiaohai Yang and Kemin Wang and Jianbo Liu},
  journal={The Analyst},
  year={2013},
  volume={138 17},
  pages={5146-50}
}
A highly sensitive dynamic light scattering (DLS) assay for glucose detection without interference from ascorbic acid was demonstrated based on mercaptophenylboronic acid functionalized gold nanoparticles (MPBA-AuNPs). The stable, water-solubility MPBA-AuNPs were synthesized using facile and mild method. In the presence of glucose, specific binding between glucose and boronic acids resulted in the aggregation of MPBA-AuNPs. Thus, glucose could be detected by monitoring the average particle size… CONTINUE READING